Archive for the ‘Health News’ Category

The rate is improved survival of patients with breast cancer?

Monday, May 3rd, 2010

There is a new study showing that the survival rate of women with recurrent breast cancer has been improving in the last two decades, but also cautions that more studies are needed.

Sharon H. Giordano, MDLa lead author and assistant professor in the Department of Breast Medical Oncology at M. D Anderson answered several questions hacerca of this study.

What was the goal of this destudio?

The goal of this study was to determine whether the survival rate in patients with recurrent breast cancer had improved (the recurrent cancer is cancer that returns after his initial diagnosis).

As obtained that information?

The researchers analyzed data from 834 patients of M. D Anderson who had had recurrent cancer developed between th December 1974 and November 2000.

The major objective of this study was to evaluate the association between the year in which recurrence was detected and subsequent survive. Patients were divided into five groups basing on the year in which occurred recurrence, and survival was compared between these five groups.

They found?

Although our findings are suggestive and not conclusive, our data suggest that the prognosis of patients with recurrent breast cancer has improved from 1974 to 2000.

Our analysis shows that there is a significant improvement in survival rates over the five groups, in more recent patients who live more noticeable after diagnosis of recurrence.

The following are the survival rates were diagnosticaos patients with recurrent breast cancer and specific period:

* 10% for 1974-1979 patients
* 14% for 1980-1984 patients
* 22% for 1985-1989 patients
* 29% for 1990-1994 patients
* 44% for 1995-2000 patients

The more recent the recurrence group had better prognostic variables, and a longer life span, this is due in part to advances in drugs and treatments. The most favorable variables include:

* A smaller size of the tumor
• A lower level of disease status
* Less involved lymph nodes
* Disease-free interval longer
* Tumors with positive estroneno receptors (these are tumors that use estrogen to grow).
* Tumors that do not involve major organs

It is estimated that there has been a risk reduction of 1% to 2% for each year it increases, although the change was not statistically highly significant. This statistic is consistent with data Seet (database of the results found by the National Cancer Institute Surveillance, Epidemilogy and End Results)

That current statistics indicate breast cancer?

In 2004, approximately 217.440 new cases of breast cancer were diagnosed in the United States, and 40.580 women are expected to die due to metastasis, this according to the American Cancer Society.

How conclusive are the results?

Due to the inherent difficulties faced in determining changes in survival time, we urge that these results are interpreted cautiously.

Although the strength of this study includes a large patient poblacin is needed extensive follow up (mean 9.3 years) and uniform initial stages follow-up tests, the study is limited to the problems inherited in elanalisis of survival data time.

For example, improvements in radiographic techniques and more precise imaging techniques may change the distribution of the phases. Small metastases that may have been detected with modern imaging techniques 90 could have passed without notice in the ’70s. Thus some patients were diagnosed at 70 could have been bad clasificdos saying Dela had early disease. This would result in apparent poorer prognosis of the patient group in 1970.

In addition, improvements in radiographic imaging could have resulted in more diagnoses of recurrent disease temprenaos. This could give a misleading appearance of improved survival.

What could be responsible for increasing survival?

There has been a marked increase through time on the number of drugs available to treat cancer. One of the largest increases took place in the decade of the 90s with drugs such as taxanes, vinorelbine, capecitabine, Herceptin, aromatase inhibitors and pamidronate.

Therapeutic advances have also been having an impact on the survival rate among women with breast cancer. For example, two began in the early tests involving 70 adjuvant chemotherapy (chemotherapy before surgery) these treatments were shown to have adjuvant chemotherapy buenosresultados as to the time improvement and disease-free survival.

As this study will help future research?

Regardless of progress, the improvements in survival rates in patients with recurrent breast cancer or metastatic have been difficult to establish.

The mortality of breast cancer has been in decline. From 1995-1999, rates of breast cancer have declined about 3.2% a year. But still remains not clear whether eldescenso of deaths from cancer are due to a higher proportion of patients diagnosed with early stages of the disease or improvement in treatment.

With these data, we urge them to become more recurdos to clarify whether advances in therapy have led the desupervivencia improvements in the rate of recurrent breast cancer women.

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A vaginal gel against AIDS

Thursday, April 29th, 2010

Researchers at Tulane University (USA) led by Ronald Veazey have used a protein substance (T-1249) on monkeys in order to assess the impact on a vaginal infection.
This protection would protect the three variations of AIDS.

The mechanism appears to be the inhibition of receiving site of viruses from the surface of immune cells. This receptor is common with many variations of the virus.

According to the production cost of the freeze, it could be an effective method of protection against HIV infection of women during sex.

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The scam of self-medication

Thursday, April 29th, 2010

Pigeons, that is how you could call the targets of this lucrative market.

Our Minister of Health, Roselyne Bachelot has vowed in 2007 to promote self-medication. This is for patients to get directly to the pharmacy of drugs to treat common disorders and benign, without a doctor.

While the idea may seem consistent with some sides (avoid the phrase “mandatory” for doctors to obtain medications), the consequences and context of its implementation are not.

Solid die refunds: Numerous drugs are no longer supported, or less taken over the past 2 years. Officially, it’s for “medical service rendered inadequate”, and to alleviate the famous hole in Social Security. In a mercantile logic, this “insufficient medical service rendered” is translated automatically by a significant increase in the price for the patient. The prices of medicines “repaid” as determined and negotiated by the government and pharmaceutical companies. These prices become “free” once they are delisted.

Freedom has a price we are told … and it is also true for prescription drugs. “Today in France” in a survey published in late December that the finding. One pharmacy to another, there is the doubling of price for example for the Nurofen (against migraine) € 1.48 in the Paris region, to 2.90 € in Montpellier, or the tablets Rennie ( cons stomach pains) of 4.90 € in the Paris region to 9.55 € in Strasbourg.

The causes? An aggressive marketing campaign conducted smoothly. It is “Le Parisien” that explains, information from a frame (anonymized of course) high up in a pharmaceutical, “laboratories prefer to send their medical representatives to discuss prices directly with pharmacists. For, thanks to their technical sales, he embobinent! “.

We learn that the price increase is organized in areas less competitive. Pharmacies are classified and codified. The pharmacies listed as “A” are those in city centers, the more competitive, those of the suburbs are classified “B”, the campaigns for “C”. The price increases with the letter of the alphabet.

Well, good news will still, the Parisian informs us that France is trying to sell part of the 94 million vaccinations (but nobody wants it, character “moderate” this flu is now proven).

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A long-term study will analyze the relationship between mobile phone use and its health consequences

Monday, April 26th, 2010
  • Publication Date: April 25, 2010

A long-term study at Imperial College London (United Kingdom) with around 250,000 people aged 18 to 69 years will examine the relationship that may exist between the use of mobile phones and development of health problems long term, such as neurological diseases or certain types of cancer.

Work is expected to have a duration of between 20 and 30 years, since all previous studies on the effects of using these devices have been made in the short term and at most only lasted 10 years. Unless your relationship with an increased risk of traffic accidents, there is no evidence to determine a risk to health. However, there still exist some uncertainties about the effects of using mobile phones, as some diseases take years to develop and so far there are few people who have used these phones for so long.

You have to make a long-term monitoring to identify whether there are any possible health impact of this new technology as used at present, said Mireille Toledano, co-investigator of the study. “By observing a large number of people across Europe over a long period of time, we can build a valuable picture of whether there is any link between mobile phone use and health problems in the long term,” added another the study’s authors, Paul Elliott.

The citizens participating in the project COSMOS must complete an online questionnaire on mobile phone use, health and lifestyles. Be studied and if they use these devices to make calls, send messages or download data. Also take into account whether the users have the phone in his pants, his breast pocket or use the hands-free. It also will track any disease that developed during this entire period, for which changes will be addressed symptoms, including headaches and sleep disorders, and explore whether they relate to mobile phone use.

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Influenza A in Spain affects 8 out of 100,000

Monday, April 26th, 2010

The incidence rate of influenza A during the last week has fallen to 8 per 100,000 people infected, according to the National Epidemiological Surveillance Network of the Instituto de Salud Carlos III, obtained through its network of sentinel physicians. Tomorrow marks the first anniversary of the first cases of influenza A in Spain, found in travelers from Mexico, where the epidemic originated.

The Ministry of Health confirmed the first affected by the influenza A in Spain on 27 April last year, a 23 year old was admitted to the Hospital of Almansa (Albacete). That person happened thousands of cases per week, which reached its peak with the highest incidence in mid-November, when flu cases detected 372.70 per 100.0000 inhabitants, most affected by the H1N1 virus. However, a year after influenza A and is no longer predominant in Spain and, in fact, there are up to five communities (Aragón, Baleares, Castilla y León, Valencia and Murcia) reported no influenza activity during the week of 12 to 17 April, the latest data available to the agency under the Ministry of Science and Innovation.

Communities with more cases of flu this week are Catalonia, with 34.33 cases per 100,000 population, and the Canary Islands (29.67), followed by Extremadura (18.6), Asturias (12.93) and Cantabria (11 , 3). With one more testimonial activity present data other communities like the Basque Country (4.4), Madrid (3.17) and Andalusia (1.08). All networks point system and an incidence of influenza with values pre-epidemic period and in fact, the national rate is the same as a year ago and just before the start of the pandemic. In addition, the Carlos III highlights a progression of the disease “stable” in most of the territory subject to surveillance.

During this year saw a total of 271 deaths related to influenza, according to the latest health bulletin on December 30th. However, the Carlos III recognizes that as of late December, five weeks after the peak of the pandemic wave, there was an excess mortality which coincided with a notable drop in temperatures and the publication of a cold weather alert, on days 19 and December 20, 2009.

The first death from influenza in Spain took place on June 30, 2009 in Madrid, a 20 year old Moroccan national who was 28 weeks pregnant and came to give birth at the Hospital Gregorio Maranon de Madrid. His case was controversial because it would die weeks later also his son, Rayan, a medical error in the same hospital.

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Discovered a substance in breast milk kills cancer cells

Wednesday, April 21st, 2010

A group of researchers from the University of Lund and Gothenburg University in Sweden has discovered that a substance found in milk can destroy cancer cells, as enshrined in the journal PLoS ONE. ” The discovery was made while scientists were studying the antibacterial properties of breast milk. This very special substance, known as “Hamlet” (Human Alpha-lactalbumin Made Lethal to Tomour cells), was discovered in breast milk for several years, but so far has not been possible to test its effectiveness in humans. This study showed that patients with bladder cancer who were treated with the substance killed the cancer cells removed through the urine after each treatment, so there is hope that they will become a medicine for cancer treatment in the future. “Hamlet” is composed of a protein and a fatty acid found naturally in breast milk, although not yet known whether the substance is formed naturally in the milk or may be formed in the acidic environment of the stomach babies. Moreover, Hamlet kills only cancer cells and does not affect healthy cells. Laboratory experiments have shown that this substance kills 40 different types of cancer. The researchers will now study its effect on skin cancer, tumors in the mucous membranes and brain tumors. Breast milk out for other benefits already known. According to the World Health Organization (WHO), strengthens baby’s immune system and helps maintain good health throughout life, as were infants of adults who often have lower blood pressure, less cholesterol and lower rates of overweight, obesity and type 2 diabetes.

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The vitamins and calcium supplements may reduce breast cancer risk

Tuesday, April 20th, 2010

The risk of breast cancer would decrease with vitamins and calcium supplements. This is the main conclusion of a study at the School of Medicine Ponce de Puerto Rico, announced during the annual meeting of the American Cancer Society. “It’s not an immediate effect,” said Jaime Matta, head of the study, “however, we observed a long-term effect.”

The researcher said the findings suggest that calcium supplements act to increase DNA repair capacity, a complex biological process involving more than 200 proteins that, if altered, may lead to cancer development. “This process involves at least five separate mechanisms and is critical for maintaining genomic stability. When the DNA is not repaired, leads to the mutation that leads to cancer,” said Matta.

The study involved 268 women with breast cancer and 457 healthy controls. The older women were more likely to develop breast cancer, family history, were not breastfeed their children and had lower DNA repair capacity.

Vitamin supplements appear to reduce breast cancer risk by about 30% and calcium, 40%. After taking into account the level of DNA repair capacity, calcium supplements failed to protect. However, it maintained the link between vitamin supplements and reduced risk of breast cancer. “We’re not talking about megadoses of these vitamins and calcium supplements, so this is a way to reduce the risk,” he said Matta.

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Eating soy after menopause helps reduce the risk of osteoporosis

Tuesday, April 20th, 2010

The intake of soy and hormone replacement therapy after menopause reduces the risk of osteoporosis. It also protects against the toxicity of-amyloid peptide in Alzheimer’s disease and currently studying a possible preventive effect against type 2 diabetes.

Dr. José Viña Ribes, Faculty of Medicine and Dentistry, University of Valencia, these data highlighted during the conference “The benefits of soy food supplements for longevity genes” in the Royal Academy of Pharmacy.

“The use of estrogen in menopausal women can be detrimental and therefore used soy isoflavones,” said Vina Ribes, which is positioned for food supplemented with soybean against the use of genistein as a drug. The doctor stressed that it is advisable to eat these foods in small amounts several times a day.

For his part, Dr. Lisandro Boscá Gomar, director of the Institute of Biomedical Research Alberto Sols, gave a speech entitled “Inflammation and pathogenicity. The inflammatory response in cardiovascular disease and aging.” Boscá addressed the issue of inflammatory conditions as a cause of 70% -80% of diseases among which Alzheimer’s disease, anaphylaxis, atherosclerosis, Crohn’s disease or ischemic damage. The doctor also stressed the importance of inflammatory cells such as monocytes, macrophages and neutrophils, as well as the transcription factors PPAR and LXR.

Eating soy after menopause helps reduce the risk of osteoporosis

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