Archive for the ‘Medical research’ Category

Are you Lacking The H2o Purification Method Which Transforms Your Pores and skin Hair And Well being?

Friday, November 19th, 2010

The simplest achievable way that could add further years for your lifestyle is always to drink pure clean h2o. Despite the fact that several folks physical exercise day-to-day and diet plan to remain match and healthy inside the hope of prolonging their lifestyle; they fail to appreciate that the addition of poisons to their physique will probably be unhealthy. The h2o that we see and use each day is becoming an increasing number of contaminated. The an increasing number of harmful toxins which might be incorporated within our consuming drinking water will leave us open to numerous illnesses, to prevent this you require a drinking water purification procedure which will get rid of this contamination and return it towards the purity it as soon as was.

Our drinking water can include as much as 2,000 identified carcinogenic compounds. The vast majority of these are man-made. Sadly, the vast majority of individuals fail to know there’s no new drinking water, what goes down the drain ultimately gets recycled. Your local municipal drinking water plant most likely recycles the identical drinking water repeatedly. For many from the time, the drinking water utility vegetation managed to accomplish an output of healthy drinking water, nevertheless each and every so frequently a spike of contamination seems.

A lot from the filtration gear that these vegetation use has been in use for an extended interval of time. It’s really difficult for them to maintain up using the quantity of chemicals which are incorporated within our drinking water provide every day. Even though the degree of contamination keeps growing their budgets don’t, this puts you and i in danger of receiving polluted drinking water within our houses. Each and every time you take a drink on this drinking water your wellness suffers.

It’s impossible to flush poisons out of the entire body using the liquid that contains an equal quantity of poisons. You’re not just at threat whenever you drink but additionally whenever you cook, shower or bathe on this drinking water. Showering on this drinking water is really much more harmful than consuming a single glass of this drinking water.

There are lots of various types of drinking water purification processes. Some are much more effective than other people, contrary towards the universal belief you don’t have to get rid of everything from the drinking water. Together with the contamination are important minerals which are important for the wellness. You will find some filters that get rid of these together with the pollution leaving you with demineralized drinking water. Consuming this kind of drinking water over an extended interval will result in wellness difficulties.

To be able to prevent this kind of filter it’s really essential that you simply do your study. An superb way of discovering just how much and what contaminants are eliminated from any specific filter would be to read the manufacturers’ information sheet. Any reputable manufacturer is going to be only too pleased to supply you having a copy. You need to be wary of producers who make exaggerated claims concerning the effectiveness of their item.

The addition of a drinking water purification procedure for your household may have a marked impact in your pores and skin, hair and most importantly your wellness. You’ll be in a position to see and taste the distinction inside your drinking water. Keep in mind you’re creating an investment within the continuing wellness of your self and your loved ones.

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Olive oil to prevent breast cancer

Tuesday, April 27th, 2010

Breast cancer affects between 20% and 25% of Spanish women. But thanks to medical advances and public awareness about the importance of early diagnosis, Spain is one of the European countries with a lower incidence of breast cancer. One of the cornerstones of research in this field is prevention. An initiative that brings together biologists, oncologists and the Inter-Organization of Spanish Olive Oil combines efforts and has launched a project of clinical trials on the effect of virgin olive oil in the prevention of this cancer. It tries to demonstrate, within five years, that a moderate intake of olive oil can slow the progression of the tumor.

Preventing food

The action of mechanisms that counteract the harmful role of fat would be key to confirm that olive oil is an ideal food for the prevention and the fight against breast cancer. From previous research, the Multidisciplinary Group for the Study of Breast Cancer (GMECM) analyze the influence of normal components of human nutrition in cancer progression and make scientific views regarding the health of the population or the risk of this disease. In addition, it will detect the molecular changes that repeated use olive oil results in the human genome and, in particular genes involved in breast cancer. The researchers caution that excessive consumption of seed oil extracted can be harmful, but tests conducted in vitro and experimental studies with human cell lines to confirm all these points.
The HER2
As a precedent to this impulse in the investigation of olive oil, a study of the Catalan Institute of Oncology (ICO) envisioned two years ago that between 20% and 30% of breast cancers that express HER2 molecule are sensitive to effect of this type of oil. The work, led by Javier A. Menendez, speculated on the possibility that the Mediterranean diet, rich in olive oil, reduced the risk of breast cancer. Menendez theory, then much discussed, was that the active compounds of olive oil only affect certain types of tumors.

It is known that one of the drugs tested against breast cancer, Herceptin, HER2 acts on the molecules of tumor cells, which are responsible for cell growth. ICO researchers thought then that olive oil may also act on this molecule. After isolating several compounds olive oil extra virgin found two types that inactivate HER2 in tumor cells. This oil, being pressed without heat, it keeps most of the compounds from olives that are lost in the olive oil processing.

The researchers confirmed that in animals with carcinoma tumors became less evil by eating large amounts of extra virgin olive oil. However, Menendez says that “this does not mean that the intake of extra virgin olive oil prevents or treatment of breast cancer as those compounds, when ingested, do not always act the same way.”

Preventing food-

The action of mechanisms that counteract the harmful role of fat would be key to confirm that olive oil is an ideal food for the prevention and the fight against breast cancer. From previous research, the Multidisciplinary Group for the Study of Breast Cancer (GMECM) analyze the influence of normal components of human nutrition in cancer progression and make scientific views regarding the health of the population or the risk of this disease. In addition, it will detect the molecular changes that repeated use olive oil results in the human genome and, in particular genes involved in breast cancer. The researchers caution that excessive consumption of seed oil extracted can be harmful, but tests conducted in vitro and experimental studies with human cell lines to confirm all these points.

The HER2

As a precedent to this impulse in the investigation of olive oil, a study of the Catalan Institute of Oncology (ICO) envisioned two years ago that between 20% and 30% of breast cancers that express HER2 molecule are sensitive to effect of this type of oil. The work, led by Javier A. Menendez, speculated on the possibility that the Mediterranean diet, rich in olive oil, reduced the risk of breast cancer. Menendez theory, then much discussed, was that the active compounds of olive oil only affect certain types of tumors.

A Mediterranean diet has significant protective effects against cancer, heart disease and aging

It is known that one of the drugs tested against breast cancer, Herceptin, HER2 acts on the molecules of tumor cells, which are responsible for cell growth. ICO researchers thought then that olive oil may also act on this molecule. After isolating several compounds olive oil extra virgin found two types that inactivate HER2 in tumor cells. This oil, being pressed without heat, it keeps most of the compounds from olives that are lost in the olive oil processing.

The researchers confirmed that in animals with carcinoma tumors became less evil by eating large amounts of extra virgin olive oil. However, Menendez says that “this does not mean that the intake of extra virgin olive oil prevents or treatment of breast cancer as those compounds, when ingested, do not always act the same way.”
Increases survival rate
Although the survival rate of sick people has increased in recent years, breast cancer is the most common tumor among Spanish women. Latest figures show that in our country some 16,000 cases are diagnosed annually, representing 24.6% of all tumors that afflict women. It is the leading cause of death and the most common malignant tumor in the world after lung cancer. Most of these cases are diagnosed mainly between 45 and 65.

Nevertheless, the number of cases is slowly increasing thanks to the progressive aging population and early diagnosis, While the success of treatments has allowed the number of deaths from this cause falls.

BACKGROUND oleic acid

Scientists in Chicago (USA) were the first to propose that a Mediterranean diet rich in olive oil could reduce the risk of breast cancer. The key ingredient of olive oil, the oleic acidAppeared as the main suspect. Laboratory experiments on breast cancer cells made at the Northwestern University allowed these researchers show that oleic acid does reduce dramatically the levels of a gene linked to the disease.

In the journal “Annals of Oncology” stated that the study carried out was interesting, but cautioned that more research needed. Scientists in Chicago have confirmed that oleic acid reduces the levels of Her-2/neu gene, present in more than a fifth of patients with breast cancer and is associated with highly aggressive tumors. But not only did oleic acid suppress activity of the gene, but also boosted the effectiveness of a new drug used against breast cancer (Herceptin).

From the ICO, Javier A. Menendez tried these studies in key positive “findings underpin epidemiological studies that show that the Mediterranean diet has significant protective effects against cancer as well against coronary disease and aging. “However, Tim Key, deputy director of the epidemiology unit of Cancer Research UK (Oxford, UK), maintained that the only risk factors established for this cancer are obesity and alcohol, and the data showed no direct evidence that olive oil reduces the risk of breast cancer.

Following the results of the work of Menendez, Key said: “This new study shows interesting effects of olive oil on cancer cells under laboratory conditions, but calls for more studies to prove” if it is of some importance in cancer breast cancer in particular. ” The newly created GMECM intends to reveal these unknowns.

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Relationship between cancer and genetic disorders

Tuesday, April 27th, 2010

Cancer is a disease with wide molecular basis, since tumor cells are characterized by numerous structural and functional changes with respect to normal cells. These variations are not necessarily the same for each tissue and tumor. Although most cancer processes follow a common pattern, there are particular genes associated with various tumors, some very frequent in the Spanish population, which give the wearer a small risk of developing cancer, diabetes or cardiovascular disease. All these characteristics make cancer a genetic study of complex and expensive process, but knowing these genes would help in the development of prevention programs and better treatment strategies and early diagnosis with a simple blood test.
Different tumors with similar genetic characteristics

Different tumors in different tissues and patients of different ages stand out repetitive patterns of genes in common. In DNA there are multiple copies of each gene, some of them only have two copies while many others have a large number scattered throughout the genome. The number of copies is one of the factors that determines the rate of synthesis of the proteins they encode. Thus, changes in the number of copies will affect the concentration of protein in the cell and thus modulate its function.

A major study conducted by scientists from USA, Japan, Canada and Spain has shown that various tumor types share very similar genetic characteristics. The work has been published in the journal “Nature” and it has involved scientists at the Hospital Vall d’Hebron and the Institut d’Oncologia Vall d’Hebron, Barcelona. For the investigation we have analyzed more than 3,000 tumor samples from 26 types of cancer. As explained by Josep Tabernero, an oncologist at the hospital, “we analyzed copies of the genes of somatic cells (which form the growth of tissues and organs of a living being, from embryonic stem cells) tumor and were compared with germ cells ( containing genetic material) from the same patient. ”

Abnormalities were detected in the number of regions in tumor cells, either due to lack or excess. The most interesting discovery is that the change in the number of copies is found in several tumors of different cancers to assume 75% of the changes common to all tumors and only 25% of tumor-specific alterations. In the study, 122 were also found new genomic regions likely to have a relationship with the tumoral process. However, the authors claim that only 25% know of the possible genes involved in cancer and still more research is needed.

The director of the Institut d’Oncologia Vall d’Hebron, Josep Baselga, in this respect that, “the end of the day, cancer is a disease of the genome. It breaks down and ends up developing a tumor.”

In the DNA is stored almost all the hereditary information of the organism, related to structural and functional characteristics, so that if you analyze and compare the genome of different cells, healthy and tumor, there are some common areas and other different between them. This allows determination of common genetic characteristics in tumor cells, not present in healthy cells, which help to identify common patterns related to the tumor process.
Genetic markers for breast and colon

The number of repetitions of specific regions in the genome is not the only implication of genetics in cancer, because there are specific genes associated with various tumors. One such group is known as low-penetrance genes that are common in the population and give the wearer a small risk of developing a certain disease. Not only are related to cancer disease, but can also facilitate the development of other diseases such as diabetes or cardiovascular problems. However, it is a necessary interaction of more than one risk to be considered for a particular disease.

In relation to breast cancer, seven were known far penetrance genes. However, a recent study conducted by the International Consortium of Breast Cancer (BCAC) has unveiled two new genes involved. The BCAC is an international consortium involving 27 research groups for breast cancer. Among them, three Spanish organizations: the National Cancer Centre (CNIO), Hospital Universitario La Paz Hospital in Madrid and Oviedo Monte Naranco.

The study, published in the journal “Nature Genetics”, it concludes that these two new genes and are nine penetrance genes are associated with breast cancer. As the number of genes discovered, can be designed better therapies and diagnostic for prevention. It is estimated that they participate in a 6% in the genetic component of this tumor.

Similarly, another study by Spanish researchers, in collaboration with other countries, reveals new genetic markers that increase the risk of developing colon cancer. These new markers can be helpful in determining the risk of developing the disease in people with colon cancer runs in your family. José Augusto García Agundez, Professor of Pharmacology at the University of Extremadura and collaborator in the study, explains that the new genetic markers “allow the realization of early diagnosis of the disease in a routine and massive, with a simple blood test .

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