Olive oil to prevent breast cancer

Breast cancer affects between 20% and 25% of Spanish women. But thanks to medical advances and public awareness about the importance of early diagnosis, Spain is one of the European countries with a lower incidence of breast cancer. One of the cornerstones of research in this field is prevention. An initiative that brings together biologists, oncologists and the Inter-Organization of Spanish Olive Oil combines efforts and has launched a project of clinical trials on the effect of virgin olive oil in the prevention of this cancer. It tries to demonstrate, within five years, that a moderate intake of olive oil can slow the progression of the tumor.

Preventing food

The action of mechanisms that counteract the harmful role of fat would be key to confirm that olive oil is an ideal food for the prevention and the fight against breast cancer. From previous research, the Multidisciplinary Group for the Study of Breast Cancer (GMECM) analyze the influence of normal components of human nutrition in cancer progression and make scientific views regarding the health of the population or the risk of this disease. In addition, it will detect the molecular changes that repeated use olive oil results in the human genome and, in particular genes involved in breast cancer. The researchers caution that excessive consumption of seed oil extracted can be harmful, but tests conducted in vitro and experimental studies with human cell lines to confirm all these points.
The HER2
As a precedent to this impulse in the investigation of olive oil, a study of the Catalan Institute of Oncology (ICO) envisioned two years ago that between 20% and 30% of breast cancers that express HER2 molecule are sensitive to effect of this type of oil. The work, led by Javier A. Menendez, speculated on the possibility that the Mediterranean diet, rich in olive oil, reduced the risk of breast cancer. Menendez theory, then much discussed, was that the active compounds of olive oil only affect certain types of tumors.

It is known that one of the drugs tested against breast cancer, Herceptin, HER2 acts on the molecules of tumor cells, which are responsible for cell growth. ICO researchers thought then that olive oil may also act on this molecule. After isolating several compounds olive oil extra virgin found two types that inactivate HER2 in tumor cells. This oil, being pressed without heat, it keeps most of the compounds from olives that are lost in the olive oil processing.

The researchers confirmed that in animals with carcinoma tumors became less evil by eating large amounts of extra virgin olive oil. However, Menendez says that “this does not mean that the intake of extra virgin olive oil prevents or treatment of breast cancer as those compounds, when ingested, do not always act the same way.”

Preventing food-

The action of mechanisms that counteract the harmful role of fat would be key to confirm that olive oil is an ideal food for the prevention and the fight against breast cancer. From previous research, the Multidisciplinary Group for the Study of Breast Cancer (GMECM) analyze the influence of normal components of human nutrition in cancer progression and make scientific views regarding the health of the population or the risk of this disease. In addition, it will detect the molecular changes that repeated use olive oil results in the human genome and, in particular genes involved in breast cancer. The researchers caution that excessive consumption of seed oil extracted can be harmful, but tests conducted in vitro and experimental studies with human cell lines to confirm all these points.

The HER2

As a precedent to this impulse in the investigation of olive oil, a study of the Catalan Institute of Oncology (ICO) envisioned two years ago that between 20% and 30% of breast cancers that express HER2 molecule are sensitive to effect of this type of oil. The work, led by Javier A. Menendez, speculated on the possibility that the Mediterranean diet, rich in olive oil, reduced the risk of breast cancer. Menendez theory, then much discussed, was that the active compounds of olive oil only affect certain types of tumors.

A Mediterranean diet has significant protective effects against cancer, heart disease and aging

It is known that one of the drugs tested against breast cancer, Herceptin, HER2 acts on the molecules of tumor cells, which are responsible for cell growth. ICO researchers thought then that olive oil may also act on this molecule. After isolating several compounds olive oil extra virgin found two types that inactivate HER2 in tumor cells. This oil, being pressed without heat, it keeps most of the compounds from olives that are lost in the olive oil processing.

The researchers confirmed that in animals with carcinoma tumors became less evil by eating large amounts of extra virgin olive oil. However, Menendez says that “this does not mean that the intake of extra virgin olive oil prevents or treatment of breast cancer as those compounds, when ingested, do not always act the same way.”
Increases survival rate
Although the survival rate of sick people has increased in recent years, breast cancer is the most common tumor among Spanish women. Latest figures show that in our country some 16,000 cases are diagnosed annually, representing 24.6% of all tumors that afflict women. It is the leading cause of death and the most common malignant tumor in the world after lung cancer. Most of these cases are diagnosed mainly between 45 and 65.

Nevertheless, the number of cases is slowly increasing thanks to the progressive aging population and early diagnosis, While the success of treatments has allowed the number of deaths from this cause falls.

BACKGROUND oleic acid

Scientists in Chicago (USA) were the first to propose that a Mediterranean diet rich in olive oil could reduce the risk of breast cancer. The key ingredient of olive oil, the oleic acidAppeared as the main suspect. Laboratory experiments on breast cancer cells made at the Northwestern University allowed these researchers show that oleic acid does reduce dramatically the levels of a gene linked to the disease.

In the journal “Annals of Oncology” stated that the study carried out was interesting, but cautioned that more research needed. Scientists in Chicago have confirmed that oleic acid reduces the levels of Her-2/neu gene, present in more than a fifth of patients with breast cancer and is associated with highly aggressive tumors. But not only did oleic acid suppress activity of the gene, but also boosted the effectiveness of a new drug used against breast cancer (Herceptin).

From the ICO, Javier A. Menendez tried these studies in key positive “findings underpin epidemiological studies that show that the Mediterranean diet has significant protective effects against cancer as well against coronary disease and aging. “However, Tim Key, deputy director of the epidemiology unit of Cancer Research UK (Oxford, UK), maintained that the only risk factors established for this cancer are obesity and alcohol, and the data showed no direct evidence that olive oil reduces the risk of breast cancer.

Following the results of the work of Menendez, Key said: “This new study shows interesting effects of olive oil on cancer cells under laboratory conditions, but calls for more studies to prove” if it is of some importance in cancer breast cancer in particular. ” The newly created GMECM intends to reveal these unknowns.

Post to Twitter Post to Facebook Post to Google Buzz Post to Yahoo Buzz Post to MySpace Post to Digg Post to LinkedIn Send Gmail Post to Delicious Post to Squidoo Post to Bebo Post to Plurk Post to Diigo Post to FriendFeed Mixx This Post Post to Ping.fm Post to Reddit Post to Slashdot Post to StumbleUpon Post to Technorati

Tags: , ,

One Response to “Olive oil to prevent breast cancer”

  1. Pearline Kiesow says:

    After reading this post I found this is very helpful and what a great post it is

Leave a Reply


Home   |   Sitemap   |   Privacy Policy   |   Terms   |   Contact   |   Blog   |   Advertise With Us